Cellular Imaging Systems
Cellular Imaging Systems
High-Content Screening (HCS) is an advanced technique that utilizes automated microscopy and sophisticated image analysis to explore cellular behaviors and functions in depth.
Examining multiple cellular parameters simultaneously—HCS offers a comprehensive view of how cells respond to different treatments and conditions.
Molecular Devices provide high-content imaging and HCS solutions, ranging from automated digital microscopy to high-throughput confocal imaging systems with modern machine learning analysis software.
High-content Imaging
Maximize workflow efficiency and experimental design.
- ImageXpress HCS.ai
- ImageXpress Confocal HT.ai
- ImageXpress Micro Confocal
- ImageXpress Micro 4
- ImageXpress Pico
Imaging Acquisition & Analysis Software
Software which can solve complex image analysis problems by utilizing advanced artificial intelligence and customized analysis protocols.
- MetaXpress Acquire Software
- IN Carta Image Analysis Software
- StratoMineR Software
- CellReporterXpress Software
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| ImageXpress HCS.ai | ImageXpress Confocal HT.ai | ImageXpress Micro Confocal | ImageXpress Micro 4 | ImageXpress Nano | ImageXpress Pico | |
| CAMERA | • >5 mega pixel sCMOS sensor with large sensor size (224mm²) • >3 log dynamic range with 16bit detector, 95% peak quantum efficiency |
• >4 megaPixel sCMOS sensor • >3 log dynamic range with 16bit detector |
• >4 megaPixel sCMOS sensor • >3 log dynamic range with 16bit detector |
• >4 megaPixel sCMOS sensor • >3 log dynamic range with 16bit detector |
CMOS | CMOS |
| OBJECTIVES |
• 6-position automated objective changer • High NA air objectives: 2X–60X (up to 0.85 NA) • Extra long working distance objectives 20X–60X (up to 0.7 NA) • Water immersion (20x, 40x, 60x) |
•Air (2x-100x) • Water immersion (20x, 40x, 60x) • Oil (40x, 60x, 100x) |
• Air (1x-100x) • Oil (40x, 60x, 100x) • Water immersion (20x, 40x, 60x) |
• Air (2x-100x) • Oil (40x, 60x, 100x) |
• Air (2x–60x) | • Air (2.5x–63x) |
| AUTOFOCUS | Hardware + Image Autofocus | Hardware + Image Autofocus | Hardware + Image Autofocus | Hardware + Image Autofocus | Hardware + Image Autofocus | Hardware + Image Autofocus |
| PLATES SUPPORTED | Up to 1536-well plates | Up to 1536-well plates | Up to 1536-well plates | Up to 1536-well plates | Up to 1536-well plates | Up to 384-well plates |
| 96-Well Plate Scan Time, 2 Colors, 1 Site/Well | 1.5 min | 2 min | 2 min | 2 min | 4 min | 8 min |
| Maximum Illumination Channels | 7 | 7 | 5 | 5 | 5 | 6 |





