Proteomix® HIC Butyl
With butyl group chemically attached to the modified non-porous poly(styrene divinylbenzene) (PS/DVB) beads, Proteomix® HIC Butyl columns provide high resolution hydrophobic interaction separation for biomolecules such as mAb, ADCs and their fragments. With butyl group chemically attached to the modified non-porous poly(styrene divinylbenzene) (PS/DVB) beads, Proteomix® HIC Butyl columns provide high resolution hydrophobic interaction separation for biomolecules such as mAb, ADCs and their fragments.
MonomixTM MC SEC Resins
With proprietary surface modification that minimizes non-specific binding, MonomixTM MC SEC resins are highly stable over a broad pH tolerance range (1-14), an advantage over silica-based SEC resins, and compatible with many commonly used organic solvents and aqueous buffers.
ADCs Solution
A full Antibody Drug Conjugates (ADCs) chromatographic separation solution includes Zenix®-C SEC for analysis of ADCs aggregate, monomer, fragment and free drug, Proteomix® HIC Butyl and RP-1000 for Drug to Antibody Ratio (DAR) analysis, and Proteomix® and Antibodix® IEX for ADCs charge variants studies.
Featured Products
MonomixTM MC SEC Resins
With proprietary hydrophilic surface modification that minimizes non-specific binding, Sepax’s MonomixTM MC SEC resins are highly stable over a variety of operational conditions with broad pH tolerance range (1-14), an advantage over silica-based SEC resins, and compatible with many commonly used organic solvents and aqueous buffers.
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SRT® SEC Phases
Unique size exclusion phases of high stability, high capacity, high resolution and maximum recovery for biological molecules, such as proteins, nucleic acids, peptides, polysaccharides as well as water soluble synthetic polymers, bacteria, and nanomaterials. SRT SEC phases offer widest pore size selection of 100, 150, 300, 500, 1000 and 2000 Å.
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Carbomix® Phases
Made of narrow-dispersed, spherical, low cross-linking polystyrene/divinylbenzene (PS/DVB) particles. Surfaces functional groups are sulfonic acid (-SO3H), or metal ions, such as calcium (Ca+2). The PS/DVB support has cross-linking degree of 5%, 8% and 10%. The particle size selection is 3, 5 and 10 µm for analytical and preparative separations of carbohydrates, organic acids, peptides, and nucleic acids.
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Zenix® SEC Phases
Made of 3 µm silica particles, Zenix SEC packing is a breakthrough technology for size exclusion chromatography. Combination of 3 µm silica particle size and proprietary surface technology enables Zenix SEC phases achieved highest separation efficiency and resolution for biological molecules and water soluble polymers. Available pore sizes of Zenix packings are 100, 150 and 300Å.
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MonomixTM IEX Resins
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Antibodix® Phase
Antibodix are specially designed for high resolution, high efficiency and high recovery separations of antibodies. The packing support is composed of a rigid, spherical, highly cross-linked poly(styrene divinylbenzene) (PS/DVB) non-porous bead. The uniform beads have the particle size selection of 1.7, 3, 5 and 10 µm.
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Proteomix® IEX Phases
A breakthrough technology of achieving combined high ion-exchange capacity and high resolution for the non-porous resins. With the particle size selection of 1.7, 3, 5 and 10 µm, Proteomix ion-exchange phases are specially designed for high resolution, high efficiency and high recovery separations of proteins, oligonucleotides and peptides. The packing support is composed of a rigid, spherical, highly cross-linked poly(styrene divinylbenzene) (PS/DVB) non-porous particle.
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GlycomixTM SAX Phase
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PolyRPTM Resins
Compared to silica-based reversed phase resins, Sepax’s PolyRPTM are PS/DVB-based reversed phase resins that are stable at extreme pH (1-14) with a similar separation efficiency and better selectivity. They can withstand high temperatures up to 200 °C (operating temperature up to 80 °C), and compatible with many commonly used organic solvents and aqueous buffers.
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